Lack of support for bexarotene as a treatment for Alzheimer's disease
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چکیده
منابع مشابه
Lack of support for bexarotene as a treatment for Alzheimer's disease.
Bexarotene has been reported to reduce brain amyloid-β (Aβ) levels and to improve cognitive function in transgenic mouse models of Alzheimer's disease (AD). Four groups failed to fully replicate the primary results but the original authors claimed overall support for the general conclusions. Because of its potential clinical importance, the current work studied the effects of bexarotene using t...
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ژورنال
عنوان ژورنال: Neuropharmacology
سال: 2016
ISSN: 0028-3908
DOI: 10.1016/j.neuropharm.2015.04.020